10 Minutes on foot to Termini Station
3 Metro stops to the Spanish Steps
15 Minutes on foot to San Lorenzo
5 Metro stops to the Vatican Museum
12 Minutes on foot to Piazza della Repubblica


Santa Maria Inn Rome is a smart, stylish yet simple guest house accommodation in the centre of Rome offering great value at low prices and the possibility do go semi-self-catering with our kitchenette corners in every room and shared main kitchen. All our rooms are en suite, decorated in a very elegant 21st century mode and with all your basic comforts and mod cons taken care of. See our Rooms & Services page for more details


Right now you’re looking at the official website of the Santa Maria Inn in Rome, with our VAT number at the bottom and our own secure online booking form - that means you’re dealing directly with us and not a third party such as a portal site or online travel agency. While we do work with third parties, none of them have permission to undercut the published room rates here on our official site, so remember, booking directly with us guarantees the best available rates for our rooms.


In the heart of the city atop the Esquiline Hill, the Santa Maria Inn Guest House Rome is in a central location well connected to everything the eternal city has to offer. With the trendy neighbourhoods of Monti on one side and San Lorenzo on the other; and Termini, Vittorio Emanuele, Cavour and Repubblica metro stations within easy walking distance, you’ll never be more than half an hour from any of Rome’s landmarks.
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